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  • Assessment of Vascular Patency and Inflammation with Intravascular Optical Coherence Tomography in Patients with Superficial Femoral Artery Disease Treated with Zilver PTX Stents

    • Posted: 03/03/2020
    • Author:

      Taylor Hoyt, Marc D. Feldman, Sercan Okutucu, Vasili Lendel, Konstantinos Marmagkiolis, Victoria McIntosh, Ismail Ates, Gulcan Kose, David Mego, Andre Paixao, Cezar Iliescu, Jongwan Park, Mohammad Shaar, Recep Avci, Austin McElroy, Jouke Dijkstra, Thomas E. Milner and Mehmet Cilingiroglu

    • 2020CRM

    Highlights

    • Intravascular optical coherence tomography can measure features which are proxies for inflammatory response.
    • Zilver PTX stents show evidence of inflammatory response at 12 months.
    • Stent cross-sectional area increased over time even as the lumens narrowed over time.

     

    Abstract

    Purpose

    Zilver PTX nitinol self-expanding drug-eluting stent with paclitaxel coating is effective for treatment of superficial femoral artery (SFA) disease. However, as with any stent, it induces a measure of vascular inflammatory response. The current clinical trial ( NCT02734836 ) aimed to assess vascular patency, remodeling, and inflammatory markers with intravascular optical coherence tomography (OCT) in patients with SFA disease treated with Zilver PTX stents.

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