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Ventricular Interaction for TTVr Patients Raises 1-Year Risks in German Registry Study

Jun 16, 2025 by
Natalie Morrison, CRTonline.org

Ventricular interaction was associated with increased 1-year risk of death and heart failure hospitalization for transcatheter tricuspid valve repair (TTVr) patients in a German registry study.

Older PCI Patients at Greater Risk, Frailer Patients Even More So: Registry Study

Jun 16, 2025 by
Natalie Morrison, CRTonline.org

Frailty is common in older patients undergoing percutaneous coronary intervention (PCI) in the US, with a “clear gradient of increasing risk” based on frailty status, according to a new registry analysis of more than 1.3 million patients.

Review Redefines Heart Failure With Improved Ejection Fraction as a Remission State, Not Recovery

Jun 16, 2025 by
Will Chu, CRTonline.org

A review redefines heart failure with improved ejection fraction (HFimpEF) as a distinct clinical phenotype with persistent risks despite apparent recovery in heart function.

Long-Term Study Links COVID-19 With Coronary Microvascular Dysfunction

Jun 16, 2025 by
Bailey G. Salimes, CRTonline.org

Patients with the coronavirus disease 2019 (COVID-19) have long-term reduced stress perfusion, indicative of coronary microvascular dysfunction (CMD) and reduced left ventricular (LV) function, compared with healthy patients, a new case-control study shows.

New Adverse Events Reported in First Year of Evoque System Approval for Patients With TR: MAUDE Database Analysis

Jun 12, 2025 by
Bailey G. Salimes, CRTonline.org

A new database analysis of Evoque system usage in patients undergoing transcatheter tricuspid valve replacement reveals several adverse events not reported in the original trial for approval of the system.

Trillium Device Safe, Effective for Patients With Tricuspid Regurgitation

Jun 10, 2025 by
Will Chu, CRTonline.org

New research findings point to the safety and efficacy of a novel heterotopic valve device designed to treat patients with severe tricuspid regurgitation (TR) who are ineligible for traditional surgical or interventional approaches: the Trillium Device.

ACPMDs Devices Increase Success Rates in Complex Coronary CTO Procedures

Jun 10, 2025 by
Will Chu, CRTonline.org

New research has found that using advanced calcific plaque modification devices (ACPMDs) significantly improves outcomes in patients undergoing percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) with severe calcification.

Study Finds Intermediate RVPAC Levels Best Indicate T-TEER Suitability in Patients With Severe TR

Jun 09, 2025 by
Will Chu, CRTonline.org

New study findings reveal that assessing right ventricular-pulmonary artery coupling (RVPAC) helps predict which patients with severe tricuspid regurgitation (TR) could benefit from transcatheter tricuspid valve edge-to-edge repair (T-TEER).

Trial Suggests Finerenone Decreases CV Event Risk in Vulnerable Patients Who Have HF With Improved Ejection Fraction

Jun 09, 2025 by
Will Chu, CRTonline.org

A new analysis reveals that patients with heart failure with improved ejection fraction (HFimpEF) remained at high risk of cardiovascular events, as researchers emphasized the condition’s continued management despite left ventricular EF (LVEF) improvement, but finerenone may mitigate this risk.

Study Finds Fewer Clots, Less Bleeding With Low-Dose DOAC Post-Watchman Device

Jun 09, 2025 by
Will Chu, CRTonline.org

Patients undergoing left atrial appendage occlusion (LAAO) with a Watchman device may experience a significantly lower risk of early device-related thrombus (DRT) when managed with low-dose direct oral anticoagulation (LD-DOAC) compared to dual antiplatelet therapy (DAPT).

PFO Closure Reduces Risk of Recurrent Ischemic Stroke vs Medical Therapy in Older Patients: Medicare Analysis

Jun 09, 2025 by
Natalie Morrison, CRTonline.org

Patent foramen ovale (PFO) closure reduces the risk of recurrent ischemic stroke for older patients compared with medical therapy alone, according to a new real-world analysis of Medicare beneficiaries.

Watchman FLX Has Fewer 1-Year Risks Than Predecessor, No Differences in Mortality: Wide-Scale Registry Analysis

Jun 09, 2025 by
Natalie Morrison, CRTonline.org

The next generation Watchman FLX transcatheter left atrial appendage occlusion (LAAO) device is associated with significantly fewer risks of major adverse events and stroke at 1-year compared with the previous Watchman device in a new wide-scale US registry study.

Study Finds Complete Revascularization Associated With Better Outcomes in Heart Attack Patients

Jun 05, 2025 by
Will Chu, CRTonline.org

A new study suggests complete revascularization (CR) is linked to significantly improved outcomes in the treatment of patients who experience heart attack with multivessel disease (MVD).

TEER Safe and Effective for Primary Tricuspid Regurgitation: Registry Study

Jun 05, 2025 by
Natalie Morrison, CRTonline.org

Transcatheter edge-to-edge repair (TEER) is safe and effective for the treatment of primary tricuspid regurgitation (TR) in a new international registry study, including durable 1-year results.

Worse Patient Outcomes, Higher Costs in Waiting to Perform AVR in Patients With AS: Database Study

May 22, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Aortic valve replacement (AVR) is best performed before symptom onset to improve outcomes in patients with aortic stenosis (AS) and reduce healthcare costs, a new study shows.

Coronary Function Testing Safe, Effective, Improves Quality of Life in ANOCA Patients: ILIAS-ANOCA Trial

May 22, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Patients with angina and non-obstructive coronary arteries (ANOCA) can be safely and feasibly given routine ad-hoc coronary function testing (CFT) during invasive coronary angiography (ICA), according to results from the ILIAS ANOCA trial.

Combined Registry Study Finds PCBs vs SCBs Demonstrate Similar 2-Year Outcomes in Patients With CAD

May 22, 2025 by
Will Chu, CRTonline.org

Research comparing paclitaxel and sirolimus-coated balloons (PCB and SCB), used in coronary artery disease (CAD) treatment, finds similar outcomes between the two balloons with respect to MACE at 2-years follow-up.

EARLY TAVR Trial Shows Early TAVR Improves Cardiac Damage From Baseline at 2-Years Post-Procedure

May 22, 2025 by
Bailey G. Salimes, CRTonline.org

PARIS – Results from a 2-year follow-up analysis of the EARLY-TAVR trial show patients who have early transcatheter aortic valve replacement (TAVR) show improvement in cardiac damage compared with baseline, but patients in the clinical surveillance (no TAVR) group have worsening cardiac damage.

CMD Associated With Persistent Angina, Reduced Quality of Life in PCI Patients

May 22, 2025 by
Will Chu, CRTonline.org

An international study suggests that coronary microvascular dysfunction (CMD) is a major contributor to residual angina and reduced quality of life in patients who undergo successful percutaneous coronary intervention (PCI).

FFR and IVUS Show Similar Long-Term Outcomes in Coronary Stenosis Trial

May 22, 2025 by
Will Chu, CRTonline.org

Fractional flow reserve (FFR)-guided treatment and intravascular ultrasound (IVUS)-guided treatment for intermediate coronary stenosis result in similar long-term clinical outcomes, a new study shows.

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