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Despite Recent Advances in LAAO, Questions Remain Over Patient, Device Selection: State-of-the-Art Review

Jan 14, 2025 by
Nathan Gray, CRTonline.org

While multiple advancements in left atrial appendage occlusion (LAAO) devices have emerged for stroke prevention and arrhythmia therapy, several unanswered questions remain, specifically regarding the patient and device selection and the management of complications, according to a new review.

HF Patients With Prior MI See No Clinical Benefit from Revivent TC Anchor System vs Medical Therapy Alone: ALIVE Trial

Jan 14, 2025 by
Natalie Morrison, CRTonline.org

Heart failure patients who suffered prior myocardial infarction and anterior scarring saw no improvements in clinical outcomes when treated with the Revivent TC anchor system verses guideline-directed medical therapy alone in the ALIVE trial, despite reductions in left ventricular dimensions.

Study Proposes Demographic-Based Approach to Improve Hypertrophic Cardiomyopathy Diagnosis

Jan 13, 2025 by
Will Chu, CRTonline.org

A new study suggests the introduction of personalized thresholds for diagnosing hypertrophic cardiomyopathy (HCM) in proposals that challenge long-standing one-size-fits-all diagnostic standards.

Early Kidney Declines Associated with Finerenone, No Cause for Concern, Study Concludes

Jan 13, 2025 by
Will Chu, CRTonline.org

A new study suggests that patients assigned to finerenone are more likely to experience an initial decline in estimated glomerular filtration rate (eGFR) between randomization and one month compared to placebo.

Review Bares the Hidden Costs of Life-Saving Heart Failure Medications

Jan 13, 2025 by
Will Chu, CRTonline.org

Findings from a recent review have shed further light on the financial burden of heart failure (HF) medications on patients, as well as the systemic barriers that hinder cost-effective treatment.

Aspirin for Treatment of ASCVD has Similar Outcomes in Women vs Men: ADAPTABLE Secondary Analysis

Jan 06, 2025 by
Bailey G. Salimes, CRTonline.org

No sex-specific differences are noted in the effectiveness and safety of two doses of aspirin for secondary prevention of atherosclerotic cardiovascular disease (ASCVD) events, a secondary analysis of the ADAPTABLE trial shows.

CVD Risk is Not Increased in Patients Taking Anti-CGRP mAbs vs OnabotulinumtoxinA for Migraines in Florida Cohort Study

Jan 06, 2025 by
Bailey G. Salimes, CRTonline.org

Medicare patients are not at greater risk for cardiovascular disease (CVD) when taking anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) for migraines, compared with onabotulinumtoxinA treatment, shows a cohort study.

Non-Trial SAVR Patients Have Comparable Mortality, Fewer Strokes Than Trial Patients From PARTNER 3 and Evolut Low Risk: Cross-Sectional Study

Jan 06, 2025 by
Bailey G. Salimes, CRTonline.org

Low-risk, trial-like patients undergoing surgical aortic valve replacement (SAVR) during the trial enrollment period have similar 30-day rates of mortality, but lower rates of stroke, compared with patients in the SAVR arm of the PARTNER 3 and Evolut Low Risk trials, a cross-sectional analysis shows.

AI Assists in Predicting Incident Hypertension, Adverse Outcomes: Cohort Study

Jan 03, 2025 by
Bailey G. Salimes, CRTonline.org

Incident hypertension and patients at risk of hypertension-related outcomes can be predicted by an artificial intelligence-enhanced electrocardiography (AI-ECG) model, AI-ECG risk estimator to predict incident hypertension (AIRE-HTN), results from a cohort study show.

Redo TAVR With SAPIEN 3 Associated With Downsizing, Under-Expansion “Complexities”: Patient Analysis

Dec 23, 2024 by
Nathan Gray, CRTonline.org

Redo transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 (S3) valve presents challenges, according to a new analysis of patient data that also shows downsizing is frequent, and under-expansion may lead to suboptimal hemodynamics.

Study Suggests Radial Access Superior to Femoral Route for Secondary Use in TAVR Procedures

Dec 23, 2024 by
Will Chu, CRTonline.org

New study findings challenge established practices in transcatheter aortic valve replacement (TAVR), as researchers demonstrate that transradial secondary access (TR-SA) significantly reduces complications compared to traditional transfemoral secondary access (TF-SA).

High-Output Circulatory Support is Redefining Safety in Left Main Coronary Interventions: Magenta Medical Study

Dec 23, 2024 by
Will Chu, CRTonline.org

A first-in-human study has demonstrated the exceptional safety and efficacy of the Magenta Elevate mechanical circulatory support (MCS) device during high-risk percutaneous coronary interventions (HR-PCI) involving the left main coronary artery (LM).

Angiography Provides Additional Insights for IVUS-Guided PCI: FLAVOUR Trial Post-Hoc Analysis

Dec 23, 2024 by
Natalie Morrison, CRTonline.org

Angiography-based physiological assessments can offer additional prognostic insights for patients undergoing intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI), according to a post-hoc analysis of the FLAVOUR trial.

ECLS Unlikely to Benefit Any Infarct-Related CS Subpopulations: ECLS-SHOCK Machine Learning Analysis

Dec 23, 2024 by
Natalie Morrison, CRTonline.org

A new machine learning assessment of the ECLS-SHOCK study found there is a “low likelihood” that any subpopulation of infarct-related cardiogenic shock (CS) patients will respond to extracorporeal life support (ECLS).

Discussion on Arrhythmia Monitoring After Stroke: ACC Expert Consensus

Dec 20, 2024 by
Bailey G. Salimes, CRTonline.org

Cardiac rhythm monitoring after stroke continues to be a topic of debate as improved monitoring strategies increase likelihood of arrhythmia detection post-stroke, but impacts on secondary stroke prevention are still unclear, reports an expert consensus.

Hypertension, Obesity Strong Risk Factors for New-Onset HF: U.K. Biobank Study

Dec 20, 2024 by
Bailey G. Salimes, CRTonline.org

Hypertension and obesity are the strongest risk factors for new-onset heart failure (HF) in both men and women, but women are still at greater risk than men, a new analysis of the U.K. Biobank shows.

Potential Risk Factors for Progressive Ascending Aorta Dilation in BAV Patients Undergoing TAVR Identified: Exploratory Analysis

Dec 16, 2024 by
Natalie Morrison, CRTonline.org

A subset of bicuspid aortic stenosis patients undergoing transcatheter aortic valve replacement may be at increased risk for progressive ascending aorta dilation, according to a new exploratory analysis of 61 patients.

Should Sex be a Factor in Deciding 3VD Patients’ Revascularization Strategy?

Dec 16, 2024 by
Natalie Morrison, CRTonline.org

Women with 3-vessel coronary artery disease have similar outcomes to men following placement of a drug-eluting stent using percutaneous coronary intervention but fare worse with coronary artery bypass grafting.

Revolutionary Study Maps Navitor Transcatheter Aortic Valve Geometry Using CT Imaging

Dec 09, 2024 by
Will Chu, CRTonline.org

In the first study of its kind, scientists have conducted a computed tomography (CT) analysis of the in vivo frame geometry of the Navitor intra-annular self-expanding valve (SEV).

NCL Location Makes No Difference in Outcomes of Complete Revascularization for STEMI with MVD: COMPLETE Trial Sub Analysis

Dec 09, 2024 by
Natalie Morrison, CRTonline.org

Complete revascularization, including both culprit and non-culprit lesions (NCLs), is beneficial for ST-segment elevation myocardial infarction (STEMI) patients with multivessel disease (MVD), regardless of NCL location, according to a new analysis of the COMPLETE trial.

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