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  • Association of high level of hs-CRP with in-stent restenosis: A case-control study

    • Posted: 07/24/2019
    • Author:

      Mojtaba Baktashian, Sara Saffar Soflaei, Negin Kosari, Mansoor Salehi, Alireza Khosravi, Maliheh Ahmadinejad, Mohsen Moohebati, Mahmood Ebrahimi, Farzad Rahmani, Ramin Khameneh-Bagheri, Mostafa Ahmadi, Fatemeh Sadabadi, Maryam Tayefi, Suzan Bazhdanzadeh, Gordon A. Ferns, Seyed Mohammad Hashemi, Alireza Pasdar and Majid Ghayour-Mobarhan

    • 2019CRM

    Highlights

    • Presence of diabetes mellitus, previous implanted stent type and hs-CRP were the most important factors associated to occurrence of ISR.
    • Cut-off value of hs-CRP associated to ISR occurrence was lower than cut-off value defined before as a predicting factor for CHD.
    • In individuals hs-CRP > 2.64 mg/dL addition to presence of DM, bare stent and higher TG was associated with ISR.
    • In individuals with hs-CRP < 2.64 mg/dL, ISR was only associated with DM presence.
    • There was no association found between statin and ARBs and ISR occurrence.

    Abstract

    Background

    In-stent restenosis (ISR) is one adverse outcome of coronary stent implantation. Although using drug-eluting stents has reduced the rate of ISR, it remains a major problem. Here, we have investigated the relationship between several patient characteristics including serum high sensitive C-reactive protein (hs-CRP) and ISR.

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