Drug-Eluting Versus Bare-Metal Stents in Older Patients: A Meta-Analysis of Randomized Controlled Trials
Highlights
- • Drug-eluting stents (DES) were associated with low major adverse cardiovascular events (MACE).
- • Major bleeding events were similar between DES and bare-metal stents.
- • Short dual-antiplatelet therapy (≤6 months) with DES was associated with low MACE.
- • High bleeding rates were evident with longer dual-antiplatelet therapy duration.
Abstract
Background
Despite the high prevalence of ischemic heart disease in older patients, there is a substantial lack of evidence to guide clinical decision-making in this population. Hence, we performed a meta-analysis to determine the safety and efficacy of percutaneous coronary intervention (PCI) with drug-eluting stents (DES) versus bare-metal stents (BMS).