Renal Denervation in the Management of Hypertension: A Meta-Analysis of Sham-Controlled Trials
Highlights
- • In patients with hypertension, renal denervation resulted in a significant reduction in both ambulatory and office blood pressure.
- • No difference in adverse outcomes including myocardial infarction, stroke and hypertensive crisis/emergency was noted.
- • Renal denervation is safe and effective technique to reduce BP in patients with hypertension.
Abstract
Introduction
Sympathetic renal denervation (RD) can potentially reduce blood pressure (BP) in people with resistant hypertension (RH) and uncontrolled hypertension (UH). While a large sham-controlled trial (SCT) showed similar outcomes of RD vs. sham control, in the recent trials, RD was effective in reducing BP in hypertensive people. We performed a meta-analysis of SCTs of RD vs. sham in hypertensive patients.