Saphenous Vein Graft Sacrifice Following Native Vessel PCI is Safe and Associated with Favourable Longer-Term Outcomes
Highlights
- • IIn patients with saphenous vein graft (SVG) failure, PCI of the native vessel is undertaken to facilitate more durable results.
- • However, if the SVG remains patent, residual competitive flow presents a potential risk for early target lesion failure (TLF).
- • This is the first study (n = 33) to describe the safety and longer-term outcomes of deliberate SVG closure to mitigate this risk.
- • In a selected population, we found that SVG closure was safe and associated with a high success rate (97.0%).
- • Over a mean follow up of 602 (± 393) days from the date of SVG closure, the incidence of TLF of the reconstructed native vessel was 9.1% (n = 3).
- • Our results call for larger randomised trials to establish the benefit of this approach.
Abstract
Background
Competitive flow from saphenous vein grafts (SVG) that remain patent following percutaneous coronary intervention (PCI) of the native vessel may compromise durability of the reconstructed vessel. SVG sacrifice has been advocated, but the safety and longer-term outcomes of this are unknown.