Transcatheter Aortic Valve Replacement in Low-Risk Patients: A Meta-Analysis of Randomized Controlled Trials
Highlights
- • TAVR was not associated with change of mortality
- • TAVR was associated with lower risk of acute kidney injury
- • TAVR was associated with lower risk of new-onset atrial fibrillation
- • TAVR was associated with lower risk of bleeding
- • TAVR was associated with higher risk of moderate-severe paravalvular leak, and permanent pacemaker insertion
Abstract
Introduction
Transcatheter aortic valve replacement (TAVR) has become the standard treatment option for patients with symptomatic severe aortic stenosis (AS) with high surgical risk and a reasonable option for intermediate surgical risk as an alternative to surgical aortic valve replacement (SAVR). The role of TAVR in lower risk patients is less established but has been the focus of recent randomized controlled trials (RCTs). We performed a meta-analysis of RCTs to assess TAVR outcomes among low surgical risk patients.