Both genetic and social factors should play a joint role in boosting the accuracy of risk modelling for coronary heart disease (CHD), said the authors of a new analysis of the ‘All of Us’ (AoU) program, stressing that racial identity is a crucial driver behind bigger social burden.
A recent review reveals the significant risks heart failure patients face if they discontinue long-term drug treatments, which can include a rapid return to baseline and worsening rebound.
The review focuses on patients with heart failure with reduced ejection fraction (HFrEF) and warns of persistent cardiovascular deterioration and a gradual decline from long-term benefits for those abruptly stopping foundational heart medications, even for short periods.
“The totality of available evidence points to a meaningful clinical deterioration within a few weeks following the withdrawal for most drugs that have been evaluated for the treatment of heart failure,” said the authors of the paper, which appears in the Journal of the American College of Cardiology.
“These findings suggest that that current emphasis on the implementation of foundational drugs needs to include an equally important emphasis to avoid even short-term gaps in treatment.”
A new article offers insight on the challenges of reducing mortality rates in patients with heart failure with mildly reduced ejection fraction (HFmrEF) and preserved ejection fraction (HFpEF).
In newly published research, researchers identify a genetic variant in the BAG3 gene that they think plays a complex, dual role in the risk spectrum of dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM).
In the post-pandemic U.S., cardiovascular death rates are 1.5 times higher in rural areas compared with urban areas, a brief report shows, and socioeconomic factors are the most significant cause for these outcomes.
An ‘optimal’ procedural result of grade of 0/1+ regurgitation after tricuspid edge-to-edge repair is associated with improved outcomes and functional status, according to an analysis of real-world patient data from the Spanish TRI-SPA registry.
A new study outlines the substantial improvements in quality of life, symptom severity and exercise capacity among patients implanted with the Coronary Sinus Reducer in treating patients with refractory angina.
Newly published findings reveal that the coronary sinus reducer significantly reduces angina symptoms and improves quality of life for patients with coronary microvascular dysfunction.
In patients undergoing percutaneous coronary interventions (PCI) for significant coronary artery disease (CAD), AI-based quantitative coronary angiography (AI-QCA) is non-inferior to optical coherence tomography (OCT) guided PCI, according to results from the FLASH trial.
Nathan Gray, CRTonline.org
Will Chu, CRTonline.org
Natalie Morrison, CRTonline.org
Bailey G. Salimes, CRTonline.org
Michael Mahmoudi, MD - R Hahn, et al. NEJM 2024 Online
Michael Mahmoudi, MD - B Anderson, et al.; Lancet 2024 Online
Michael Mahmoudi, MD - P Genereux, et al.; NEJM 2024 Online
Michael Mahmoudi, MD - V Kunadian, et al.; NEJM 2024 Online
EINPresswire
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Should guidelines include asymptomatic patients with severe aortic stenosis as eligible for TAVR?
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Jose L. Diz Ferre and Eugene H. Blackstone
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